Characterizing Outflow Graft Narrowing over Time

PurposeCases of pump dysfunction due to outflow graft (OG) anastomosis obstruction related serous fluid accumulation have been reported but the rate occlusion and actual frequency asymptomatic OG diminution is not known.MethodsThis was a multicenter retrospective analysis patients on HeartMate II (HMII) or 3 (HM3) support surviving at least 180 days with one chest computed tomography (CT) scan 6 months, 1, 2, and/or years postoperative. Patients torsion were excluded. The diameter measured its narrowest region; region categorized as external (EOG), mid-graft, within 2 cm aortic anastomosis. Mixed models repeated measure linear regression used assess change over time, 14 mm reference. Using measure, modelled for freedom from death, admission HF low flow alarms hazard ratio [95% CI presented].ResultsOf 71 included herein, 25% 75% HMII HM3 median [25th, 75th] 1230 [703,1592] days. CT count [1,2] per patient. At follow-up, small (1-3 mm, table), statistically significant reductions in noted (Figure). narrowing 7% [0%, 20%]. Time device implant most contributing factor (p<0.001) while wrapping nonsignificantly correlated (p=0.071). Device model correlative (p=0.16). survival (HR 1.04 [0.81-1.3]), stroke 0.94 [0.78-1.1]) admissions heart failure 1.06 [0.88-1.3]), VAD 0.93 [0.79-1.1]).ConclusionMinor irrespective LVAD model. observed degrees non-twist related-OG herein did lead increase mortality events. may be associated time. Larger sample analyses aim define that elicit dysfunction. Cases known. This presented]. Of [0.79-1.1]). Minor